Investigation of astrovirus, coronavirus and paramyxovirus co-infections in bats in the western Indian Ocean

Co-infections have a key role in virus transmission in wild reservoir hosts. We investigated the simultaneous presence of astroviruses, coronaviruses, and paramyxoviruses in bats from Madagascar, Mayotte, Mozambique, and Reunion Island. A total of 871 samples from 28 bat species representing 8 famil...

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Autores principales: Hoarau, Axel O. G., Goodman, Steven M., Al Halabi, Dana, Ramasindrazana, Beza, Lagadec, Erwan, Le Minter, Gildas, Köster, Marie, Dos Santos, Andréa, Schoeman, M. Corrie, Gudo, Eduardo S., Mavingui, Patrick, Lebarbenchon, Camille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506490/
https://www.ncbi.nlm.nih.gov/pubmed/34641936
http://dx.doi.org/10.1186/s12985-021-01673-2
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author Hoarau, Axel O. G.
Goodman, Steven M.
Al Halabi, Dana
Ramasindrazana, Beza
Lagadec, Erwan
Le Minter, Gildas
Köster, Marie
Dos Santos, Andréa
Schoeman, M. Corrie
Gudo, Eduardo S.
Mavingui, Patrick
Lebarbenchon, Camille
author_facet Hoarau, Axel O. G.
Goodman, Steven M.
Al Halabi, Dana
Ramasindrazana, Beza
Lagadec, Erwan
Le Minter, Gildas
Köster, Marie
Dos Santos, Andréa
Schoeman, M. Corrie
Gudo, Eduardo S.
Mavingui, Patrick
Lebarbenchon, Camille
author_sort Hoarau, Axel O. G.
collection PubMed
description Co-infections have a key role in virus transmission in wild reservoir hosts. We investigated the simultaneous presence of astroviruses, coronaviruses, and paramyxoviruses in bats from Madagascar, Mayotte, Mozambique, and Reunion Island. A total of 871 samples from 28 bat species representing 8 families were tested by polymerase chain reactions (PCRs) targeting the RNA-dependent RNA-polymerase genes. Overall, 2.4% of bats tested positive for the presence of at least two viruses, only on Madagascar and in Mozambique. Significant variation in the proportion of co-infections was detected among bat species, and some combinations of co-infection were more common than others. Our findings support that co-infections of the three targeted viruses occur in bats in the western Indian Ocean region, although further studies are needed to assess their epidemiological consequences. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12985-021-01673-2.
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spelling pubmed-85064902021-10-12 Investigation of astrovirus, coronavirus and paramyxovirus co-infections in bats in the western Indian Ocean Hoarau, Axel O. G. Goodman, Steven M. Al Halabi, Dana Ramasindrazana, Beza Lagadec, Erwan Le Minter, Gildas Köster, Marie Dos Santos, Andréa Schoeman, M. Corrie Gudo, Eduardo S. Mavingui, Patrick Lebarbenchon, Camille Virol J Short Report Co-infections have a key role in virus transmission in wild reservoir hosts. We investigated the simultaneous presence of astroviruses, coronaviruses, and paramyxoviruses in bats from Madagascar, Mayotte, Mozambique, and Reunion Island. A total of 871 samples from 28 bat species representing 8 families were tested by polymerase chain reactions (PCRs) targeting the RNA-dependent RNA-polymerase genes. Overall, 2.4% of bats tested positive for the presence of at least two viruses, only on Madagascar and in Mozambique. Significant variation in the proportion of co-infections was detected among bat species, and some combinations of co-infection were more common than others. Our findings support that co-infections of the three targeted viruses occur in bats in the western Indian Ocean region, although further studies are needed to assess their epidemiological consequences. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12985-021-01673-2. BioMed Central 2021-10-12 /pmc/articles/PMC8506490/ /pubmed/34641936 http://dx.doi.org/10.1186/s12985-021-01673-2 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Short Report
Hoarau, Axel O. G.
Goodman, Steven M.
Al Halabi, Dana
Ramasindrazana, Beza
Lagadec, Erwan
Le Minter, Gildas
Köster, Marie
Dos Santos, Andréa
Schoeman, M. Corrie
Gudo, Eduardo S.
Mavingui, Patrick
Lebarbenchon, Camille
Investigation of astrovirus, coronavirus and paramyxovirus co-infections in bats in the western Indian Ocean
title Investigation of astrovirus, coronavirus and paramyxovirus co-infections in bats in the western Indian Ocean
title_full Investigation of astrovirus, coronavirus and paramyxovirus co-infections in bats in the western Indian Ocean
title_fullStr Investigation of astrovirus, coronavirus and paramyxovirus co-infections in bats in the western Indian Ocean
title_full_unstemmed Investigation of astrovirus, coronavirus and paramyxovirus co-infections in bats in the western Indian Ocean
title_short Investigation of astrovirus, coronavirus and paramyxovirus co-infections in bats in the western Indian Ocean
title_sort investigation of astrovirus, coronavirus and paramyxovirus co-infections in bats in the western indian ocean
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506490/
https://www.ncbi.nlm.nih.gov/pubmed/34641936
http://dx.doi.org/10.1186/s12985-021-01673-2
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