Cargando…
Artesunate attenuates foam cell formation by enhancing cholesterol efflux
BACKGROUND: Atherosclerosis is the main cause of many cardiovascular diseases and the second leading cause of death in elderly people. The formation of intimal macrophage-derived foam cells is a major feature of early atherosclerotic lesions. Little is known about the effects of artesunate (ART) on...
Autores principales: | Qian, Yan, Xia, Li, Wei, Lai, Jiang, Weiwei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506543/ https://www.ncbi.nlm.nih.gov/pubmed/34733931 http://dx.doi.org/10.21037/atm-21-3551 |
Ejemplares similares
-
Neuropeptide Y regulates cholesterol uptake and efflux in macrophages and promotes foam cell formation
por: Cai, Yu, et al.
Publicado: (2022) -
The Oxysterol 24(S),25-Epoxycholesterol Attenuates Human Smooth Muscle–Derived Foam Cell Formation Via Reduced Low-Density Lipoprotein Uptake and Enhanced Cholesterol Efflux
por: Beyea, Michael M., et al.
Publicado: (2012) -
Spiromastixones Inhibit Foam Cell Formation via Regulation of Cholesterol Efflux and Uptake in RAW264.7 Macrophages
por: Wu, Chongming, et al.
Publicado: (2015) -
Cholesterol Efflux Capacity of Apolipoprotein A-I Varies with the Extent of Differentiation and Foam Cell Formation of THP-1 Cells
por: Yano, Kouji, et al.
Publicado: (2016) -
β(3)-Adrenoceptor activation upregulates apolipoprotein A-I expression in HepG2 cells, which might further promote cholesterol efflux from macrophage foam cells
por: Gao, Xia-qing, et al.
Publicado: (2017)