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Application of various surgical techniques in liver transplantation: a retrospective study

BACKGROUND: Surgical techniques of liver transplantation have continually evolved and have been modified. We retrospectively analyzed a single-center case series and compared the advantages and disadvantages of each method. METHODS: Six-hundred and seventy-four recipients’ perioperative data were as...

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Detalles Bibliográficos
Autores principales: Chen, Zhitao, Ju, Weiqiang, Chen, Chuanbao, Wang, Tielong, Yu, Jia, Hong, Xitao, Dong, Yuqi, Chen, Maogen, He, Xiaoshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506559/
https://www.ncbi.nlm.nih.gov/pubmed/34733919
http://dx.doi.org/10.21037/atm-21-1945
Descripción
Sumario:BACKGROUND: Surgical techniques of liver transplantation have continually evolved and have been modified. We retrospectively analyzed a single-center case series and compared the advantages and disadvantages of each method. METHODS: Six-hundred and seventy-four recipients’ perioperative data were assessed and analyzed stratified by different surgical technics [modified classic (MC), modified piggyback (MPB) and classic piggyback (CPB)]. RESULTS: MELD score and Child-Pugh scores was significantly higher in CPB groups (P=0.008 and 0.003, respectively). Anhepatic time in MPB group was longer than those in CPB group (P<0.05). The operation duration in MPB group was significantly longer than those in MC group and CPB group (P=0.003). Three patients had outflow obstruction (P=0.035). The overall survival in MPB group were better than those in MC group and CPB group in general comparison (P<0.001). In patients with preoperative creatine >120 µmol/L, the overall survival in MC group was worst (P<0.001). In patients with a high MELD score (>24), the overall survival in MPB group tended to be the best (P<0.001). CONCLUSIONS: The advantages and disadvantages are different for these three surgical techniques. A reasonable operation technique should be adopted considering the patient's unique condition to ensure the stability of hemodynamics.