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Transcription factor EB mediates oxidative stress-induced intervertebral disc degeneration via the NF-κB signaling pathway

BACKGROUND: It is well known that the intervertebral disc is aggravated by a significant increase in the number of senescent cells, and oxidative stress (OS) is related to the deterioration of this tissue. Transcription factor EB (TFEB) can protect cells from OS. Accordingly, we investigated whether...

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Detalles Bibliográficos
Autores principales: Liang, He, Liu, Zhou, Wang, Yunhao, Wang, Deguo, Tian, Jiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506563/
https://www.ncbi.nlm.nih.gov/pubmed/34733937
http://dx.doi.org/10.21037/atm-21-3756