Discovery and Characterization of Novel Antagonists of the Proinflammatory Orphan Receptor GPR84

[Image: see text] GPR84 is a poorly characterized, nominally orphan, proinflammatory G protein-coupled receptor that can be activated by medium chain length fatty acids. It is attracting considerable interest as a potential therapeutic target for antagonist ligands in both inflammatory bowel disease...

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Detalles Bibliográficos
Autores principales: Jenkins, Laura, Marsango, Sara, Mancini, Sarah, Mahmud, Zobaer Al, Morrison, Angus, McElroy, Stuart P., Bennett, Kirstie A., Barnes, Matt, Tobin, Andrew B., Tikhonova, Irina G., Milligan, Graeme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506611/
https://www.ncbi.nlm.nih.gov/pubmed/34661077
http://dx.doi.org/10.1021/acsptsci.1c00151

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