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Induction of osteoclast formation by LOX mutant (LOXG473A) through regulation of autophagy

BACKGROUND: Lysyl oxidase (LOX) has been identified to modulate osteoclast activity, so we explored the role of LOX(G473A), the highest frequency single nucleotide polymorphism in LOX, in osteoclast formation and its potential relationship to autophagy. METHODS: The ability of the LOX mutant, LOX(G4...

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Detalles Bibliográficos
Autores principales: Zhang, Bo, Luo, Chenglin, Xiao, Wenjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506719/
https://www.ncbi.nlm.nih.gov/pubmed/34734026
http://dx.doi.org/10.21037/atm-21-4474