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Cold-inducible RNA-binding protein migrates from the nucleus to the cytoplasm under cold stress in normal human bronchial epithelial cells via TRPM8-mediated mechanism

BACKGROUND: Cold-inducible RNA-binding protein (CIRP or hnRNP A18) is a multifunctional stress-responsive protein. Our previous study demonstrated that cold stress increased CIRP expression and migrated from the nucleus to the cytoplasm in airway epithelial cells. However, the mechanism through whic...

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Detalles Bibliográficos
Autores principales: Mao, Liang-Ping, Jiao, Yan, Xiang, Jian-Hua, Luo, Xin-Wei, He, Qian, Ran, Dan-Hua, Xu, Qing, Lang, Chun-Hui, Chen, Ling-Xiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506723/
https://www.ncbi.nlm.nih.gov/pubmed/34734022
http://dx.doi.org/10.21037/atm-21-4447