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Entity relation extraction from electronic medical records based on improved annotation rules and BiLSTM-CRF

BACKGROUND: Extracting entities and their relationships from electronic medical records (EMRs) is an important research direction in the development of medical informatization. Recently, a method was proposed to transform entity relation extraction into entity recognition by using annotation rules,...

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Autores principales: Chen, Tingyin, Hu, Yongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506757/
https://www.ncbi.nlm.nih.gov/pubmed/34733967
http://dx.doi.org/10.21037/atm-21-3828
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author Chen, Tingyin
Hu, Yongmei
author_facet Chen, Tingyin
Hu, Yongmei
author_sort Chen, Tingyin
collection PubMed
description BACKGROUND: Extracting entities and their relationships from electronic medical records (EMRs) is an important research direction in the development of medical informatization. Recently, a method was proposed to transform entity relation extraction into entity recognition by using annotation rules, and then solve the problem of relation extraction by an entity recognition model. However, this method cannot deal with one-to-many entity relationship problems. METHODS: This paper combined the bidirectional long- and short-term memory-conditional random field (BiLSTM-CRF) deep learning model with an improvement of sequence annotation rules, hided relationships between entities in entity labels, then the problem of one-to-many named entity relation extraction in EMRs was transformed into entity recognition based on relation sets, and entity extraction was carried out through the entity recognition model. RESULTS: Entity extraction was achieved through the entity recognition model. The result of entity recognition was transformed into the corresponding entity relationship, thus completing the task of one-to-many entity relation extraction by the improved annotation rules, the accuracy rate of proposed method reaches 83.46%, the recall rate is 81.12%, and the value of comprehensive index F1 is 0.8227. CONCLUSIONS: Through the annotation analysis of EMRs, our experimental results show that the improved annotation rules can effectively complete the task of one-to-many medical entity relation extraction from EMRs.
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spelling pubmed-85067572021-11-02 Entity relation extraction from electronic medical records based on improved annotation rules and BiLSTM-CRF Chen, Tingyin Hu, Yongmei Ann Transl Med Original Article BACKGROUND: Extracting entities and their relationships from electronic medical records (EMRs) is an important research direction in the development of medical informatization. Recently, a method was proposed to transform entity relation extraction into entity recognition by using annotation rules, and then solve the problem of relation extraction by an entity recognition model. However, this method cannot deal with one-to-many entity relationship problems. METHODS: This paper combined the bidirectional long- and short-term memory-conditional random field (BiLSTM-CRF) deep learning model with an improvement of sequence annotation rules, hided relationships between entities in entity labels, then the problem of one-to-many named entity relation extraction in EMRs was transformed into entity recognition based on relation sets, and entity extraction was carried out through the entity recognition model. RESULTS: Entity extraction was achieved through the entity recognition model. The result of entity recognition was transformed into the corresponding entity relationship, thus completing the task of one-to-many entity relation extraction by the improved annotation rules, the accuracy rate of proposed method reaches 83.46%, the recall rate is 81.12%, and the value of comprehensive index F1 is 0.8227. CONCLUSIONS: Through the annotation analysis of EMRs, our experimental results show that the improved annotation rules can effectively complete the task of one-to-many medical entity relation extraction from EMRs. AME Publishing Company 2021-09 /pmc/articles/PMC8506757/ /pubmed/34733967 http://dx.doi.org/10.21037/atm-21-3828 Text en 2021 Annals of Translational Medicine. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Original Article
Chen, Tingyin
Hu, Yongmei
Entity relation extraction from electronic medical records based on improved annotation rules and BiLSTM-CRF
title Entity relation extraction from electronic medical records based on improved annotation rules and BiLSTM-CRF
title_full Entity relation extraction from electronic medical records based on improved annotation rules and BiLSTM-CRF
title_fullStr Entity relation extraction from electronic medical records based on improved annotation rules and BiLSTM-CRF
title_full_unstemmed Entity relation extraction from electronic medical records based on improved annotation rules and BiLSTM-CRF
title_short Entity relation extraction from electronic medical records based on improved annotation rules and BiLSTM-CRF
title_sort entity relation extraction from electronic medical records based on improved annotation rules and bilstm-crf
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506757/
https://www.ncbi.nlm.nih.gov/pubmed/34733967
http://dx.doi.org/10.21037/atm-21-3828
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