TLR2 inhibition ameliorates the amplification effect of LPS on lipid accumulation and lipotoxicity in hepatic cells

BACKGROUND: Gut microbiome dysbiosis is related to the pathogenesis of nonalcoholic fatty liver disease (NAFLD), and the role of toll-like receptor 2 (TLR2) in its molecular mechanism is controversial. Here, we investigated the effects and mechanisms of Escherichia coli-derived lipopolysaccharide (L...

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Detalles Bibliográficos
Autores principales: Zhang, Liting, Xie, Zehui, Yu, Hongmiao, Du, Haoxuan, Wang, Xuqiao, Cai, Jiazheng, Qiu, Yingfei, Chen, Rui, Jiang, Xiaofeng, Liu, Zelin, Li, Yi, Chen, Tuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506759/
https://www.ncbi.nlm.nih.gov/pubmed/34733981
http://dx.doi.org/10.21037/atm-21-4012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506759/
https://www.ncbi.nlm.nih.gov/pubmed/34733981
http://dx.doi.org/10.21037/atm-21-4012

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