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DDX3X deficiency alleviates LPS-induced H9c2 cardiomyocytes pyroptosis by suppressing activation of NLRP3 inflammasome

Increasing evidence suggest that NOD-like receptor protein 3 (NLRP3) inflammasome-mediated pyroptosis may be the underlying pathological mechanism of sepsis-induced cardiomyopathy. DDX3X, an ATP-dependent RNA helicase, plays a vital role in the formation of the NLRP3 inflammasome by directly interac...

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Detalles Bibliográficos
Autores principales:	Feng, Dandan, Guo, Liang, Liu, Jing, Song, Yunxuan, Ma, Xiuyuan, Hu, Haiyang, Liu, Ju, Hao, Enkui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506920/ https://www.ncbi.nlm.nih.gov/pubmed/34650637 http://dx.doi.org/10.3892/etm.2021.10825

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