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An expedient, mild and aqueous method for Suzuki–Miyaura diversification of (hetero)aryl halides or (poly)chlorinated pharmaceuticals

The development of mild, aqueous conditions for the cross-coupling of highly functionalized (hetero)aryl chlorides or bromides is attractive, enabling their functionalization and diversification. Herein, we report a general method for Suzuki–Miyaura cross-coupling at 37 °C in aqueous media in the pr...

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Detalles Bibliográficos
Autores principales: Sharma, Sunil V., Pubill-Ulldemolins, Cristina, Marelli, Enrico, Goss, Rebecca J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506956/
https://www.ncbi.nlm.nih.gov/pubmed/34745636
http://dx.doi.org/10.1039/d1qo00919b