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Secretory mouse quiescin sulfhydryl oxidase 1 aggregates defected human and mouse spermatozoa in vitro and in vivo
A flavin-dependent enzyme quiescin Q6 sulfhydryl oxidase 1 (QSOX1) catalyzes the oxidation of thiol groups into disulfide bonds. QSOX1 is prominently expressed in the seminal plasma. However, its role in male reproduction is elusive. Here, we purified the secreted form of QSOX1, i.e., QSOX1c, from m...
Autores principales: | Wang, Tse-En, Yeh, Ling-Yu, Kuo-Kuang Lee, Robert, Lu, Chung-Hao, Yang, Tsung-Hsien, Kuo, Yu-Wen, Joshi, Radhika, Tsai, Pei-Shiue, Li, Sheng-Hsiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506963/ https://www.ncbi.nlm.nih.gov/pubmed/34667943 http://dx.doi.org/10.1016/j.isci.2021.103167 |
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