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Secretory mouse quiescin sulfhydryl oxidase 1 aggregates defected human and mouse spermatozoa in vitro and in vivo

A flavin-dependent enzyme quiescin Q6 sulfhydryl oxidase 1 (QSOX1) catalyzes the oxidation of thiol groups into disulfide bonds. QSOX1 is prominently expressed in the seminal plasma. However, its role in male reproduction is elusive. Here, we purified the secreted form of QSOX1, i.e., QSOX1c, from m...

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Detalles Bibliográficos
Autores principales: Wang, Tse-En, Yeh, Ling-Yu, Kuo-Kuang Lee, Robert, Lu, Chung-Hao, Yang, Tsung-Hsien, Kuo, Yu-Wen, Joshi, Radhika, Tsai, Pei-Shiue, Li, Sheng-Hsiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506963/
https://www.ncbi.nlm.nih.gov/pubmed/34667943
http://dx.doi.org/10.1016/j.isci.2021.103167

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