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NRF3 upregulates gene expression in SREBP2-dependent mevalonate pathway with cholesterol uptake and lipogenesis inhibition

Lipids, such as cholesterol and fatty acids, influence cell signaling, energy storage, and membrane formation. Cholesterol is biosynthesized through the mevalonate pathway, and aberrant metabolism causes metabolic diseases. The genetic association of a transcription factor NRF3 with obesity has been...

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Detalles Bibliográficos
Autores principales:	Waku, Tsuyoshi, Hagiwara, Toru, Tamura, Natsuko, Atsumi, Yuri, Urano, Yasuomi, Suzuki, Mikiko, Iwami, Takuya, Sato, Katsuya, Yamamoto, Masayuki, Noguchi, Noriko, Kobayashi, Akira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506969/ https://www.ncbi.nlm.nih.gov/pubmed/34667945 http://dx.doi.org/10.1016/j.isci.2021.103180

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