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Adolescent administration of Δ(9)-THC decreases the expression and function of muscarinic-1 receptors in prelimbic prefrontal cortical neurons of adult male mice

Long-term cannabis use during adolescence has deleterious effects in brain that are largely ascribed to the activation of cannabinoid-1 receptors (CB1Rs) by delta-9-tetrahydrocannabinol (∆9-THC), the primary psychoactive compound in marijuana. Systemic administration of ∆9-THC inhibits acetylcholine...

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Detalles Bibliográficos
Autores principales:	Garzón, Miguel, Wang, Gang, Chan, June, Bourie, Faye, Mackie, Ken, Pickel, Virginia M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506972/ https://www.ncbi.nlm.nih.gov/pubmed/34667972 http://dx.doi.org/10.1016/j.ibneur.2021.09.005

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