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Application of modified Michaelis – Menten equations for determination of enzyme inducing and inhibiting drugs
BACKGROUND: Pharmacokinetics (PK) is the process of absorption, distribution, metabolism and elimination (ADME) of drugs. Some drugs undergo zero-order kinetics (ethyl alcohol), first order kinetics (piroxicam) and mixed order kinetics (ascorbic acid). Drugs that undergo Michaelis-Menten metabolism...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507113/ https://www.ncbi.nlm.nih.gov/pubmed/34635182 http://dx.doi.org/10.1186/s40360-021-00521-x |