Exosomal miR-30d-5p of neutrophils induces M1 macrophage polarization and primes macrophage pyroptosis in sepsis-related acute lung injury

BACKGROUND: Polymorphonuclear neutrophils (PMNs) play an important role in sepsis-related acute lung injury (ALI). Accumulating evidence suggests PMN-derived exosomes as a new subcellular entity acting as a fundamental link between PMN-driven inflammation and tissue damage. However, the role of PMN-...

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Detalles Bibliográficos
Autores principales: Jiao, Yang, Zhang, Ti, Zhang, Chengmi, Ji, Haiying, Tong, Xingyu, Xia, Ran, Wang, Wei, Ma, Zhengliang, Shi, Xueyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507252/
https://www.ncbi.nlm.nih.gov/pubmed/34641966
http://dx.doi.org/10.1186/s13054-021-03775-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507252/
https://www.ncbi.nlm.nih.gov/pubmed/34641966
http://dx.doi.org/10.1186/s13054-021-03775-3

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