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SUV39H2/KMT1B Inhibits the cardiomyocyte senescence phenotype by down-regulating BTG2/PC3

Suppressor of variegation 3-9 homolog 2 (SUV39H2/KMT1B), a member of the SUV39 subfamily of lysine methyltransferases (KMTs), functions as an oncogene in various types of cancers. Here, we demonstrate a novel function of SUV39H2 that drives the cardiomyocyte aging process through BTG2. In our study,...

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Detalles Bibliográficos
Autores principales: Wang, Kan, Zhu, Qiang Zhang, Ma, Xian Tao, Cheng, Cai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507256/
https://www.ncbi.nlm.nih.gov/pubmed/34559682
http://dx.doi.org/10.18632/aging.203551