Melatonin inhibits proliferation, migration, and invasion by inducing ROS-mediated apoptosis via suppression of the PI3K/Akt/mTOR signaling pathway in gallbladder cancer cells

Background: Melatonin is an indolic compound mainly secreted by the pineal gland and plays a vital role in the regulation of circadian rhythms and cancer therapy. However, the effects of melatonin in gallbladder cancer (GBC) and the related mechanism remain unknown. Methods: In this study, the antit...

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Detalles Bibliográficos
Autores principales: Chen, Kunlun, Zhu, Pengfei, Chen, Wenhui, Luo, Kai, Shi, Xiao-Jing, Zhai, Wenlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507264/
https://www.ncbi.nlm.nih.gov/pubmed/34580235
http://dx.doi.org/10.18632/aging.203561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507264/
https://www.ncbi.nlm.nih.gov/pubmed/34580235
http://dx.doi.org/10.18632/aging.203561

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