SARS-CoV-2 causes senescence in human cells and exacerbates the senescence-associated secretory phenotype through TLR-3

Senescent cells, which arise due to damage-associated signals, are apoptosis-resistant and can express a pro-inflammatory, tissue-destructive senescence-associated secretory phenotype (SASP). We recently reported that a component of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) su...

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Detalles Bibliográficos
Autores principales: Tripathi, Utkarsh, Nchioua, Rayhane, Prata, Larissa G. P. Langhi, Zhu, Yi, Gerdes, Erin O. Wissler, Giorgadze, Nino, Pirtskhalava, Tamar, Parker, Erik, Xue, Ailing, Espindola-Netto, Jair Machado, Stenger, Steffen, Robbins, Paul D., Niedernhofer, Laura J., Dickinson, Stephanie L., Allison, David B., Kirchhoff, Frank, Sparrer, Konstantin Maria Johannes, Tchkonia, Tamar, Kirkland, James L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507266/
https://www.ncbi.nlm.nih.gov/pubmed/34531331
http://dx.doi.org/10.18632/aging.203560

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