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MSCs enhances the protective effects of valsartan on attenuating the doxorubicin-induced myocardial injury via AngII/NOX/ROS/MAPK signaling pathway
Objective: To verify if AngII/NOX/ROS/MAPK signaling pathway is involved in Doxorubicin (DOX)-induced myocardial injury and if mesenchymal stem cells (MSCs) could enhance the protective effects of valsartan (Val) on attenuating DOX-induced injury in vitro. Methods: Reactive oxygen species (ROS) form...
Autores principales: | Cheng, Dong, Tu, Wencheng, Chen, Libo, Wang, Haoren, Wang, Qinfu, Liu, Hainiang, Zhu, Ning, Fang, Weiyi, Yu, Qin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507274/ https://www.ncbi.nlm.nih.gov/pubmed/34587120 http://dx.doi.org/10.18632/aging.203569 |
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