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MSCs enhances the protective effects of valsartan on attenuating the doxorubicin-induced myocardial injury via AngII/NOX/ROS/MAPK signaling pathway

Objective: To verify if AngII/NOX/ROS/MAPK signaling pathway is involved in Doxorubicin (DOX)-induced myocardial injury and if mesenchymal stem cells (MSCs) could enhance the protective effects of valsartan (Val) on attenuating DOX-induced injury in vitro. Methods: Reactive oxygen species (ROS) form...

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Detalles Bibliográficos
Autores principales: Cheng, Dong, Tu, Wencheng, Chen, Libo, Wang, Haoren, Wang, Qinfu, Liu, Hainiang, Zhu, Ning, Fang, Weiyi, Yu, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507274/
https://www.ncbi.nlm.nih.gov/pubmed/34587120
http://dx.doi.org/10.18632/aging.203569

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