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Deficiency of miR-29b2/c leads to accelerated aging and neuroprotection in MPTP-induced Parkinson’s disease mice

Studies reveal a linkage of miR-29s in aging and Parkinson’s disease (PD). Here we show that the serum levels of miR-29s in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced PD mice exhibited dynamic changes. The role of miR-29b2/c in aging and PD was studied utilizing miR-29b2/c gene knoc...

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Detalles Bibliográficos
Autores principales: Bai, Xiaochen, Zhang, Xiaoshuang, Fang, Rong, Wang, Jinghui, Ma, Yuanyuan, Liu, Zhaolin, Dong, Hongtian, Li, Qing, Ge, Jingyu, Yu, Mei, Fei, Jian, Sun, Ruilin, Huang, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507277/
https://www.ncbi.nlm.nih.gov/pubmed/34543233
http://dx.doi.org/10.18632/aging.203545