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Nesfatin-1 facilitates IL-1β production in osteoarthritis synovial fibroblasts by suppressing miR-204-5p synthesis through the AP-1 and NF-κB pathways

The progression of osteoarthritis (OA) is mediated by adipokines, one of which is nesfatin-1, which is responsible for the production of inflammatory cytokines. However, how this molecule may affect the synthesis of the proinflammatory cytokine interleukin 1 beta (IL-1β) in OA is unclear. Our analys...

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Detalles Bibliográficos
Autores principales:	Lee, Kun-Tsan, Chen, Bo-Cheng, Liu, Shan-Chi, Lin, Yen-You, Tsai, Chun-Hao, Ko, Chih-Yuan, Tang, Chih-Hsin, Tung, Kwong-Chung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507299/ https://www.ncbi.nlm.nih.gov/pubmed/34560673 http://dx.doi.org/10.18632/aging.203559

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