Reductive enzymatic dynamic kinetic resolution affording 115 g/L (S)-2-phenylpropanol

BACKGROUND: Published biocatalytic routes for accessing enantiopure 2-phenylpropanol using oxidoreductases afforded maximal product titers of only 80 mM. Enzyme deactivation was identified as the major limitation and was attributed to adduct formation of the aldehyde substrate with amino acid residu...

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Detalles Bibliográficos
Autores principales: Rapp, Christian, Pival-Marko, Simone, Tassano, Erika, Nidetzky, Bernd, Kratzer, Regina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507385/
https://www.ncbi.nlm.nih.gov/pubmed/34635076
http://dx.doi.org/10.1186/s12896-021-00715-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507385/
https://www.ncbi.nlm.nih.gov/pubmed/34635076
http://dx.doi.org/10.1186/s12896-021-00715-5

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