Notch Intracellular Domain Plasmid Delivery via Poly(Lactic-Co-Glycolic Acid) Nanoparticles to Upregulate Notch Pathway Molecules

Notch signaling is a highly conserved signaling system that is required for embryonic development and regeneration of organs. When the signal is lost, maldevelopment occurs and leads to a lethal state. Delivering exogenous genetic materials encoding Notch into cells can reestablish downstream signal...

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Detalles Bibliográficos
Autores principales: Messerschmidt, Victoria L., Chintapula, Uday, Kuriakose, Aneetta E., Laboy, Samantha, Truong, Thuy Thi Dang, Kydd, LeNaiya A., Jaworski, Justyn, Pan, Zui, Sadek, Hesham, Nguyen, Kytai T., Lee, Juhyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507495/
https://www.ncbi.nlm.nih.gov/pubmed/34651022
http://dx.doi.org/10.3389/fcvm.2021.707897

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