Cargando…

Disruption of miRNA-mRNA Networks Defines Novel Molecular Signatures for Penile Carcinogenesis

SIMPLE SUMMARY: As there are still no biomarkers reported in clinical practice in penile cancer (PeC), we aimed to investigate and validate molecular signatures based on miRNA and mRNA profiles to identify molecular drivers and pathways involved in PeC tumorigenesis. We found eight DEmiRs and 37 DEG...

Descripción completa

Detalles Bibliográficos
Autores principales:	Furuya, Tatiane Katsue, Murta, Claudio Bovolenta, Murillo Carrasco, Alexis Germán, Uno, Miyuki, Sichero, Laura, Villa, Luisa Lina, Cardilli, Leonardo, Coelho, Rafael Ferreira, Guglielmetti, Giuliano Betoni, Cordeiro, Mauricio Dener, Leite, Katia Ramos Moreira, Nahas, William Carlos, Chammas, Roger, Pontes, José
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507530/ https://www.ncbi.nlm.nih.gov/pubmed/34638231 http://dx.doi.org/10.3390/cancers13194745

Ejemplares similares

miRNA and mRNA Expression Profiles Associated with Lymph Node Metastasis and Prognosis in Penile Carcinoma
por: Murta, Claudio B., et al.
Publicado: (2022)

deltaXpress (ΔXpress): a tool for mapping differentially correlated genes using single-cell qPCR data
por: Murillo Carrasco, Alexis Germán, et al.
Publicado: (2023)

Robot-assisted laparoscopic radical prostatectomy with early retrograde release of the neurovascular bundle and endopelvic fascia sparing
por: de Albuquerque, George Augusto Monteiro Lins, et al.
Publicado: (2017)

Long-term Treatment Outcomes Between Surgical Correction and Conservative Management for Penile Fracture: Retrospective Analysis
por: Yamaçake, Kleiton Gabriel Ribeiro, et al.
Publicado: (2013)

MicroRNA-195 acts as an anti-proliferative miRNA in human melanoma cells by targeting Prohibitin 1
por: Cirilo, Priscila Daniele Ramos, et al.
Publicado: (2017)

Extracellular Vesicles Shedding Promotes Melanoma Growth in Response to Chemotherapy
por: Andrade, Luciana Nogueira de Sousa, et al.
Publicado: (2019)

Recurrent Penile Fracture—Case Report and Alternative Surgical Approach
por: Nascimento, Bruno, et al.
Publicado: (2018)

Bilateral nephrectomy robotic-assisted laparoscopic in children with bilateral Wilms’ tumor
por: Sala, Luis Fernando Macente, et al.
Publicado: (2020)

Advances in Understanding of Penile Carcinogenesis: The Search for Actionable Targets
por: Chipollini, Juan, et al.
Publicado: (2017)

Predictive factors for prolonged hospital stay after retropubic radical prostatectomy in a high-volume teaching center
por: Coelho, Rafael F., et al.
Publicado: (2018)

Non-Coding RNA in Penile Cancer
por: Pinho, Jaqueline Diniz, et al.
Publicado: (2022)

Current concepts in multiparametric magnetic resonance imaging for active surveillance of prostate cancer
por: Cavalcante, Alexandre, et al.
Publicado: (2018)

Robot-assisted endoscopic inguinal lymphadenectomy: A review of current outcomes
por: Rodrigues, Gilberto José, et al.
Publicado: (2021)

Deregulated expression of Nucleophosmin 1 in gastric cancer and its clinicopathological implications
por: Leal, Mariana Ferreira, et al.
Publicado: (2014)

Prohibitin Expression Deregulation in Gastric Cancer Is Associated with the 3′ Untranslated Region 1630 C>T Polymorphism and Copy Number Variation
por: Leal, Mariana Ferreira, et al.
Publicado: (2014)

Clinical Characteristics and Treatment Outcomes of Patients With Advanced Germ Cell Tumor Treated at a Tertiary Cancer Center in Brazil
por: Vasconcellos, Vitor Florin, et al.
Publicado: (2019)

MicroRNA Expression Profiles in Gastric Carcinogenesis
por: Hwang, Jinha, et al.
Publicado: (2018)

Establishment and characterization of a penile cancer cell line, penl1, with a deleterious TP53 mutation as a paradigm of HPV-negative penile carcinogenesis
por: Chen, Jieping, et al.
Publicado: (2016)

MicroRNA Expression Profile in Penile Cancer Revealed by Next-Generation Small RNA Sequencing
por: Zhang, Li, et al.
Publicado: (2015)

Deciphering miRNA–Target Relationships to Understand miRNA-Mediated Carcinogenesis
por: Navarro, Alfons
Publicado: (2021)

Small non-coding RNA deregulation in endometrial carcinogenesis
por: Ravo, Maria, et al.
Publicado: (2015)

Effect of dietary components on miRNA and colorectal carcinogenesis
por: Fadaka, Adewale Oluwaseun, et al.
Publicado: (2018)

Involvement of the long noncoding RNA NEAT1 in carcinogenesis
por: Klec, Christiane, et al.
Publicado: (2018)

TINCR: An lncRNA with dual functions in the carcinogenesis process
por: Ghafouri-Fard, Soudeh, et al.
Publicado: (2020)

Role of RNA modifications in carcinogenesis and carcinogen damage response
por: Verghese, Michelle, et al.
Publicado: (2022)

Altered mRNA Expression of NFKB1 and NFKB2 Genes in Penile Lichen Sclerosus, Penile Cancer and Zoon Balanitis
por: Wierzbicki, Piotr M., et al.
Publicado: (2022)

AB053. MicroRNA expression profile in penile cancer revealed by next-generation small RNA sequencing
por: Zhang, Li, et al.
Publicado: (2016)

Integrative miRNA and mRNA analysis in penile carcinomas reveals markers and pathways with potential clinical impact
por: Kuasne, Hellen, et al.
Publicado: (2017)

MicroRNA in carcinogenesis & cancer diagnostics: A new paradigm
por: Ahmad, Javed, et al.
Publicado: (2013)

MicroRNA deregulation in nonalcoholic steatohepatitis-associated liver carcinogenesis
por: de Conti, Aline, et al.
Publicado: (2017)

Expression of Human Telomerase RNA Is an Early Event of Stomach Carcinogenesis
por: Kuniyasu, Hiroki, et al.
Publicado: (1997)

MicroRNA-449a deficiency promotes colon carcinogenesis
por: Niki, Masanori, et al.
Publicado: (2017)

CircITCH: A Circular RNA With Eminent Roles in the Carcinogenesis
por: Ghafouri-Fard, Soudeh, et al.
Publicado: (2021)

The effects of RNA editing in cancer tissue at different stages in carcinogenesis
por: Kurkowiak, Małgorzata, et al.
Publicado: (2021)

A long non-coding RNA with important roles in the carcinogenesis
por: Ghafouri-Fard, Soudeh, et al.
Publicado: (2022)

Long Non-Coding RNA MEG3 in Metal Carcinogenesis
por: Zhang, Zhuo, et al.
Publicado: (2023)

Robot - assisted laparoscopic local recurrence resection after radical prostatectomy
por: Torricelli, Fabio C. M., et al.
Publicado: (2019)

A Case Report of Syphilis That Was Difficult to Distinguish From Penile Carcinoma
por: Tomioka, Masayuki, et al.
Publicado: (2023)

Penile sparing therapy for penile cancer
por: Yao, Henry Han-I, et al.
Publicado: (2020)

miRNA Expression Characterizes Histological Subtypes and Metastasis in Penile Squamous Cell Carcinoma
por: Ayoubian, Hiresh, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_spsp9o5u6aigu81be88mgmsb93