Lost but Not Least—Novel Insights into Progesterone Receptor Loss in Estrogen Receptor-Positive Breast Cancer

SIMPLE SUMMARY: Most breast cancers co-express estrogen receptor α (ERα) and progesterone receptor (PgR). These cancers are sensitive to endocrine therapy and, in general, have superior outcomes. However, a subset of tumors expresses ERα but loses expression of PgR in various mechanisms. The process...

Descripción completa

Detalles Bibliográficos
Autores principales: Kunc, Michał, Popęda, Marta, Biernat, Wojciech, Senkus, Elżbieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507533/
https://www.ncbi.nlm.nih.gov/pubmed/34638241
http://dx.doi.org/10.3390/cancers13194755

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507533/
https://www.ncbi.nlm.nih.gov/pubmed/34638241
http://dx.doi.org/10.3390/cancers13194755

Ejemplares similares