Cargando…

Overcoming Immunotherapy Resistance by Targeting the Tumor-Intrinsic NLRP3-HSP70 Signaling Axis

SIMPLE SUMMARY: The tumor-intrinsic NLRP3 inflammasome is a newly recognized player in the regulation of tumor-directed immune responses and promises to provide fresh insight into how tumors respond to immunotherapy. This brief review discusses recent data describing how activation of the tumor-intr...

Descripción completa

Detalles Bibliográficos
Autores principales: Theivanthiran, Balamayooran, Haykal, Tarek, Cao, Linda, Holtzhausen, Alisha, Plebanek, Michael, DeVito, Nicholas C., Hanks, Brent A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507548/
https://www.ncbi.nlm.nih.gov/pubmed/34638239
http://dx.doi.org/10.3390/cancers13194753