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Overcoming Immunotherapy Resistance by Targeting the Tumor-Intrinsic NLRP3-HSP70 Signaling Axis
SIMPLE SUMMARY: The tumor-intrinsic NLRP3 inflammasome is a newly recognized player in the regulation of tumor-directed immune responses and promises to provide fresh insight into how tumors respond to immunotherapy. This brief review discusses recent data describing how activation of the tumor-intr...
Autores principales: | Theivanthiran, Balamayooran, Haykal, Tarek, Cao, Linda, Holtzhausen, Alisha, Plebanek, Michael, DeVito, Nicholas C., Hanks, Brent A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507548/ https://www.ncbi.nlm.nih.gov/pubmed/34638239 http://dx.doi.org/10.3390/cancers13194753 |
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