HER2 Signaling and Breast Cancer Stem Cells: The Bridge behind HER2-Positive Breast Cancer Aggressiveness and Therapy Refractoriness

SIMPLE SUMMARY: Breast cancer (BC) is not a single disease, but a group of different tumors, and altered HER2 expression defines a particularly aggressive subtype. Although HER2 pharmacological inhibition has dramatically improved the prognosis of HER2-positive BC patients, there is still an urgent...

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Detalles Bibliográficos
Autores principales: Pupa, Serenella M., Ligorio, Francesca, Cancila, Valeria, Franceschini, Alma, Tripodo, Claudio, Vernieri, Claudio, Castagnoli, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507865/
https://www.ncbi.nlm.nih.gov/pubmed/34638263
http://dx.doi.org/10.3390/cancers13194778

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