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Role of FGFR2c and Its PKCε Downstream Signaling in the Control of EMT and Autophagy in Pancreatic Ductal Adenocarcinoma Cells

SIMPLE SUMMARY: This work aims to assess the contribution of the aberrant expression of the mesenchymal FGFR2c and the triggering of the downstream PKCε signaling in selected cell lines from pancreatic ductal adenocarcinoma (PDAC), a malignancy characterized by acquired EMT signature and deregulated...

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Detalles Bibliográficos
Autores principales: Ranieri, Danilo, Guttieri, Luisa, Raffa, Salvatore, Torrisi, Maria Rosaria, Belleudi, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508074/
https://www.ncbi.nlm.nih.gov/pubmed/34638477
http://dx.doi.org/10.3390/cancers13194993