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RAS Mediates BET Inhibitor-Endued Repression of Lymphoma Migration and Prognosticates a Novel Proteomics-Based Subgroup of DLBCL through Its Negative Regulator IQGAP3

SIMPLE SUMMARY: The inhibitors of BET proteins represent a promising class of therapeutic agents that target the oncogenic activity of MYC and repress DLBCL cell migration, but the mechanism of such repression remains elusive. Herein, we found that BET inhibitor JQ1 abrogated the amoeboid movement o...

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Detalles Bibliográficos
Autores principales: Chen, Chih-Cheng, Hsu, Chia-Chen, Chen, Sung-Lin, Lin, Po-Han, Chen, Ju-Pei, Pan, Yi-Ru, Huang, Cih-En, Chen, Ying-Ju, Chen, Yi-Yang, Wu, Yu-Ying, Yang, Muh-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508075/
https://www.ncbi.nlm.nih.gov/pubmed/34638508
http://dx.doi.org/10.3390/cancers13195024

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