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RAS Mediates BET Inhibitor-Endued Repression of Lymphoma Migration and Prognosticates a Novel Proteomics-Based Subgroup of DLBCL through Its Negative Regulator IQGAP3
SIMPLE SUMMARY: The inhibitors of BET proteins represent a promising class of therapeutic agents that target the oncogenic activity of MYC and repress DLBCL cell migration, but the mechanism of such repression remains elusive. Herein, we found that BET inhibitor JQ1 abrogated the amoeboid movement o...
Autores principales: | Chen, Chih-Cheng, Hsu, Chia-Chen, Chen, Sung-Lin, Lin, Po-Han, Chen, Ju-Pei, Pan, Yi-Ru, Huang, Cih-En, Chen, Ying-Ju, Chen, Yi-Yang, Wu, Yu-Ying, Yang, Muh-Hwa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508075/ https://www.ncbi.nlm.nih.gov/pubmed/34638508 http://dx.doi.org/10.3390/cancers13195024 |
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