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Beta 2 Adrenergic Receptor Antagonist Propranolol and Opioidergic Receptor Antagonist Naltrexone Produce Synergistic Effects on Breast Cancer Growth Prevention by Acting on Cancer Cells and Immune Environment in a Preclinical Model of Breast Cancer

SIMPLE SUMMARY: Here, we show that propranolol, a beta blocker used to treat high blood pressure, and naltrexone, an opiate antagonist used for drug and alcohol dependence, when combined, produce marked inhibitory effects on tumor growth and tumor mass while improving the survival rate, increasing N...

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Detalles Bibliográficos
Autores principales: Murugan, Sengottuvelan, Rousseau, Bénédicte, Sarkar, Dipak K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508249/
https://www.ncbi.nlm.nih.gov/pubmed/34638341
http://dx.doi.org/10.3390/cancers13194858