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Microbe-Mediated Activation of Toll-like Receptor 2 Drives PDL1 Expression in HNSCC

SIMPLE SUMMARY: Tumors use immunosuppressive signals to evade detection by the immune system. While recurrent and metastatic head and neck squamous cell carcinoma has historically carried a poor prognosis, therapies targeting the immunosuppressive PD1:PDL1 axis have improved survival in certain pati...

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Detalles Bibliográficos
Autores principales: Mann, Jacqueline E, Ludwig, Megan L, Kulkarni, Aditi, Scheftz, Erin B, Murray, Isabel R, Zhai, Jingyi, Gensterblum-Miller, Elizabeth, Jiang, Hui, Brenner, J Chad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508280/
https://www.ncbi.nlm.nih.gov/pubmed/34638266
http://dx.doi.org/10.3390/cancers13194782