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Cholecystokinin Receptor Antagonist Improves Efficacy of Chemotherapy in Murine Models of Pancreatic Cancer by Altering the Tumor Microenvironment

SIMPLE SUMMARY: Our research team has identified the cholecystokinin-B receptor (or CCK-BR) as a novel target for treatment of pancreatic cancer. CCK-BRs are over-expressed in pancreatic cancer and activation stimulates growth in cell culture and in animal models. CCK-BRs are also expressed on pancr...

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Detalles Bibliográficos
Autores principales:	Malchiodi, Zoe X., Cao, Hong, Gay, Martha D., Safronenka, Anita, Bansal, Sunil, Tucker, Robin D., Weinberg, Benjamin A., Cheema, Amrita, Shivapurkar, Narayan, Smith, Jill P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508339/ https://www.ncbi.nlm.nih.gov/pubmed/34638432 http://dx.doi.org/10.3390/cancers13194949

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