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Platelet Inhibition Prevents NLRP3 Inflammasome Activation and Sepsis-Induced Kidney Injury
Platelets, cellular mediators of thrombosis, are activated during sepsis and are increasingly recognized as mediators of the immune response. Platelet activation is significantly increased in sepsis patients compared to ICU control patients. Despite this correlation, the role of activated platelets...
Autores principales: | Borges-Rodriguez, Marivee, Shields, Corbin A., Travis, Olivia K., Tramel, Robert W., Baik, Cedar H., Giachelli, Chelsea A., Tardo, Geilda A., Williams, Jan Michael, Cornelius, Denise C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508664/ https://www.ncbi.nlm.nih.gov/pubmed/34638670 http://dx.doi.org/10.3390/ijms221910330 |
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