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Deubiquitinating Enzyme USP8 Is Essential for Skeletogenesis by Regulating Wnt Signaling

Disturbance in a differentiation program of skeletal stem cells leads to indecorous skeletogenesis. Growing evidence suggests that a fine-tuning of ubiquitin-mediated protein degradation is crucial for skeletal stem cells to maintain their stemness and osteogenic potential. Here, we demonstrate that...

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Detalles Bibliográficos
Autores principales: Chaugule, Sachin, Kim, Jung-Min, Yang, Yeon-Suk, Knobeloch, Klaus-Peter, He, Xi, Shim, Jae-Hyuck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508692/
https://www.ncbi.nlm.nih.gov/pubmed/34638628
http://dx.doi.org/10.3390/ijms221910289