Insights into the Genetic Variations of Human Cytochrome P450 2C9: Structural Analysis, Characterization and Comparison

Cytochromes P450 (CYP) are one of the major xenobiotic metabolizing enzymes with increasing importance in pharmacogenetics. The CYP2C9 enzyme is responsible for the metabolism of a wide range of clinical drugs. More than sixty genetic variations have been identified in CYP2C9 with many demonstrating...

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Detalles Bibliográficos
Autores principales: Parikh, Sonia J., Kamat, Sumit, Phillips, Margaret, Boyson, Samuel P., Yarbrough, Thomas, Davie, Dylan, Zhang, Qinghai, Glass, Karen C., Shah, Manish B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508694/
https://www.ncbi.nlm.nih.gov/pubmed/34638547
http://dx.doi.org/10.3390/ijms221910206

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