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DNA Demethylation in the Processes of Repair and Epigenetic Regulation Performed by 2-Ketoglutarate-Dependent DNA Dioxygenases

Site-specific DNA methylation plays an important role in epigenetic regulation of gene expression. Chemical methylation of DNA, including the formation of various methylated nitrogenous bases, leads to the formation of genotoxic modifications that impair DNA functions. Despite the fact that differen...

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Detalles Bibliográficos
Autores principales: Kuznetsov, Nikita A., Kanazhevskaya, Lyubov Yu., Fedorova, Olga S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508711/
https://www.ncbi.nlm.nih.gov/pubmed/34638881
http://dx.doi.org/10.3390/ijms221910540

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