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GPR120 Inhibits RANKL-Induced Osteoclast Formation and Resorption by Attenuating Reactive Oxygen Species Production in RAW264.7 Murine Macrophages

Osteoclasts are large, multinucleated cells that are responsible for the resorption of bone. Bone degenerative diseases, such as osteoporosis, are characterized by overactive osteoclasts. Receptor activator of nuclear factor-κB (NF-κB) ligand (RANKL) binding to its receptor on osteoclast precursors...

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Detalles Bibliográficos
Autores principales: Sithole, Cynthia, Pieterse, Carla, Howard, Kayla, Kasonga, Abe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508775/
https://www.ncbi.nlm.nih.gov/pubmed/34638884
http://dx.doi.org/10.3390/ijms221910544

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