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Geranylgeraniol Inhibits Lipopolysaccharide-Induced Inflammation in Mouse-Derived MG6 Microglial Cells via NF-κB Signaling Modulation

Persistent inflammatory reactions in microglial cells are strongly associated with neurodegenerative pathogenesis. Additionally, geranylgeraniol (GGOH), a plant-derived isoprenoid, has been found to improve inflammatory conditions in several animal models. It has also been observed that its chemical...

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Detalles Bibliográficos
Autores principales: Saputra, Wahyu Dwi, Shono, Hiroki, Ohsaki, Yusuke, Sultana, Halima, Komai, Michio, Shirakawa, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508820/
https://www.ncbi.nlm.nih.gov/pubmed/34638882
http://dx.doi.org/10.3390/ijms221910543