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Geranylgeraniol Inhibits Lipopolysaccharide-Induced Inflammation in Mouse-Derived MG6 Microglial Cells via NF-κB Signaling Modulation
Persistent inflammatory reactions in microglial cells are strongly associated with neurodegenerative pathogenesis. Additionally, geranylgeraniol (GGOH), a plant-derived isoprenoid, has been found to improve inflammatory conditions in several animal models. It has also been observed that its chemical...
Autores principales: | Saputra, Wahyu Dwi, Shono, Hiroki, Ohsaki, Yusuke, Sultana, Halima, Komai, Michio, Shirakawa, Hitoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508820/ https://www.ncbi.nlm.nih.gov/pubmed/34638882 http://dx.doi.org/10.3390/ijms221910543 |
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