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N6-Isopentenyladenosine Hinders the Vasculogenic Mimicry in Human Glioblastoma Cells through Src-120 Catenin Pathway Modulation and RhoA Activity Inhibition

Background: Vasculogenic mimicry (VM) is a functional microcirculation pattern formed by aggressive tumor cells. Thus far, no effective drugs have been developed to target VM. Glioblastoma (GBM) is the most malignant form of brain cancer and is a highly vascularized tumor. Vasculogenic mimicry repre...

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Detalles Bibliográficos
Autores principales: Pagano, Cristina, Navarra, Giovanna, Pastorino, Olga, Avilia, Giorgio, Coppola, Laura, Della Monica, Rosa, Chiariotti, Lorenzo, Florio, Tullio, Corsaro, Alessandro, Torelli, Giovanni, Caiazzo, Pasquale, Gazzerro, Patrizia, Bifulco, Maurizio, Laezza, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508824/
https://www.ncbi.nlm.nih.gov/pubmed/34638872
http://dx.doi.org/10.3390/ijms221910530

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