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Regulation of Survival Motor Neuron Gene Expression by Calcium Signaling

Spinal muscular atrophy (SMA) is caused by homozygous survival of motor neurons 1 (SMN1) gene deletion, leaving a duplicate gene, SMN2, as the sole source of SMN protein. However, a defect in SMN2 splicing, involving exon 7 skipping, results in a low level of functional SMN protein. Therefore, the u...

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Detalles Bibliográficos
Autores principales:	Choi, Kwangman, Yang, Ansook, Baek, Jiyeon, Jeong, Hyejeong, Kang, Yura, Baek, Woosun, Kim, Joon-Chul, Kang, Mingu, Choi, Miri, Ham, Youngwook, Son, Min-Jeong, Han, Sang-Bae, Kim, Janghwan, Jang, Jae-Hyuk, Ahn, Jong Seog, Shen, Haihong, Woo, Sun-Hee, Kim, Jong Heon, Cho, Sungchan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508836/ https://www.ncbi.nlm.nih.gov/pubmed/34638572 http://dx.doi.org/10.3390/ijms221910234

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