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MS-275 (Entinostat) Promotes Radio-Sensitivity in PAX3-FOXO1 Rhabdomyosarcoma Cells
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma of childhood. About 25% of RMS expresses fusion oncoproteins such as PAX3/PAX7-FOXO1 (fusion-positive, FP) while fusion-negative (FN)-RMS harbors RAS mutations. Radiotherapy (RT) plays a crucial role in local control but metastatic RMS is...
Autores principales: | Cassandri, Matteo, Pomella, Silvia, Rossetti, Alessandra, Petragnano, Francesco, Milazzo, Luisa, Vulcano, Francesca, Camero, Simona, Codenotti, Silvia, Cicchetti, Francesca, Maggio, Roberto, Festuccia, Claudio, Gravina, Giovanni Luca, Fanzani, Alessandro, Megiorni, Francesca, Catanoso, Marialuigia, Marchese, Cinzia, Tombolini, Vincenzo, Locatelli, Franco, Rota, Rossella, Marampon, Francesco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508838/ https://www.ncbi.nlm.nih.gov/pubmed/34639012 http://dx.doi.org/10.3390/ijms221910671 |
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