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Chrysin Ameliorates Cyclosporine-A-Induced Renal Fibrosis by Inhibiting TGF-β(1)-Induced Epithelial–Mesenchymal Transition

Cyclosporine A (CsA) is a nephrotoxicant that causes fibrosis via induction of epithelial–mesenchymal transition (EMT). The flavonoid chrysin has been reported to have anti-fibrotic activity and inhibit signaling pathways that are activated during EMT. This study investigated the nephroprotective ro...

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Detalles Bibliográficos
Autores principales: Nagavally, Rohan Reddy, Sunilkumar, Siddharth, Akhtar, Mumtaz, Trombetta, Louis D., Ford, Sue M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508845/
https://www.ncbi.nlm.nih.gov/pubmed/34638597
http://dx.doi.org/10.3390/ijms221910252