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Donepezil Regulates LPS and Aβ-Stimulated Neuroinflammation through MAPK/NLRP3 Inflammasome/STAT3 Signaling

The acetylcholinesterase inhibitors donepezil and rivastigmine have been used as therapeutic drugs for Alzheimer’s disease (AD), but their effects on LPS- and Aβ-induced neuroinflammatory responses and the underlying molecular pathways have not been studied in detail in vitro and in vivo. In the pre...

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Detalles Bibliográficos
Autores principales: Kim, Jieun, Lee, Hyun-ju, Park, Seon Kyeong, Park, Jin-Hee, Jeong, Ha-Ram, Lee, Soojung, Lee, Heeyong, Seol, Eunyoung, Hoe, Hyang-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508964/
https://www.ncbi.nlm.nih.gov/pubmed/34638977
http://dx.doi.org/10.3390/ijms221910637