Cargando…

Curcumin and Its New Derivatives: Correlation between Cytotoxicity against Breast Cancer Cell Lines, Degradation of PTP1B Phosphatase and ROS Generation

Breast cancer is the most common cancer of women—it affects more than 2 million women worldwide. PTP1B phosphatase can be one of the possible targets for new drugs in breast cancer therapy. In this paper, we present new curcumin derivatives featuring a 4-piperidone ring as PTP1B inhibitors and ROS i...

Descripción completa

Detalles Bibliográficos
Autores principales: Kostrzewa, Tomasz, Wołosewicz, Karol, Jamrozik, Marek, Drzeżdżon, Joanna, Siemińska, Julia, Jacewicz, Dagmara, Górska-Ponikowska, Magdalena, Kołaczkowski, Marcin, Łaźny, Ryszard, Kuban-Jankowska, Alicja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508995/
https://www.ncbi.nlm.nih.gov/pubmed/34638706
http://dx.doi.org/10.3390/ijms221910368

Ejemplares similares