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Curcumin and Its New Derivatives: Correlation between Cytotoxicity against Breast Cancer Cell Lines, Degradation of PTP1B Phosphatase and ROS Generation
Breast cancer is the most common cancer of women—it affects more than 2 million women worldwide. PTP1B phosphatase can be one of the possible targets for new drugs in breast cancer therapy. In this paper, we present new curcumin derivatives featuring a 4-piperidone ring as PTP1B inhibitors and ROS i...
Autores principales: | Kostrzewa, Tomasz, Wołosewicz, Karol, Jamrozik, Marek, Drzeżdżon, Joanna, Siemińska, Julia, Jacewicz, Dagmara, Górska-Ponikowska, Magdalena, Kołaczkowski, Marcin, Łaźny, Ryszard, Kuban-Jankowska, Alicja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508995/ https://www.ncbi.nlm.nih.gov/pubmed/34638706 http://dx.doi.org/10.3390/ijms221910368 |
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