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GPR21 Inhibition Increases Glucose-Uptake in HepG2 Cells

GPR21 is a constitutively active, orphan, G-protein-coupled receptor, with in vivo studies suggesting its involvement in the modulation of insulin sensitivity. However, its precise contribution is not fully understood. As the liver is both a major target of insulin signalling and critically involved...

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Detalles Bibliográficos
Autores principales: Kinsella, Gemma K., Cannito, Stefania, Bordano, Valentina, Stephens, John C., Rosa, Arianna C., Miglio, Gianluca, Guaschino, Valeria, Iannaccone, Valeria, Findlay, John B. C., Benetti, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509304/
https://www.ncbi.nlm.nih.gov/pubmed/34639123
http://dx.doi.org/10.3390/ijms221910784