GPNMB Extracellular Fragment Protects Melanocytes from Oxidative Stress by Inhibiting AKT Phosphorylation Independent of CD44

Glycoprotein non-metastatic melanoma protein B (GPNMB) is a type I transmembrane glycoprotein that plays an important role in cancer metastasis and osteoblast differentiation. In the skin epidermis, GPNMB is mainly expressed in melanocytes and plays a critical role in melanosome formation. In our pr...

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Detalles Bibliográficos
Autores principales: Wang, Qianqian, Kuroda, Yasutaka, Yang, Lingli, Lai, Sylvia, Mizutani, Yukiko, Iddamalgoda, Arunasiri, Guo, Jiao, Yamamoto, Asako, Murase, Daiki, Takahashi, Yoshito, Xiang, Leihong, Inoue, Shintaro, Tsuruta, Daisuke, Katayama, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509362/
https://www.ncbi.nlm.nih.gov/pubmed/34639184
http://dx.doi.org/10.3390/ijms221910843

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