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Constitutively Activating Mutants of Equine LH/CGR Constitutively Induce Signal Transduction and Inactivating Mutations Impair Biological Activity and Cell-Surface Receptor Loss In Vitro

The signal transduction of the equine lutropin/choriogonadotropin receptor (eLH/CGR) is unclear in naturally occurring activating/inactivating mutants of this receptor, which plays an important role in reproductive physiology. We undertook the present study to determine whether conserved structurall...

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Detalles Bibliográficos
Autores principales: Byambaragchaa, Munkhzaya, Seong, Hoon-Ki, Choi, Seung-Hee, Kim, Dae-Jung, Kang, Myung-Hwa, Min, Kwan-Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509413/
https://www.ncbi.nlm.nih.gov/pubmed/34639064
http://dx.doi.org/10.3390/ijms221910723

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